{"id":16257,"date":"2022-03-15T12:27:06","date_gmt":"2022-03-15T12:27:06","guid":{"rendered":"https:\/\/mediahouseinternational.com\/?p=16257"},"modified":"2022-06-30T15:53:28","modified_gmt":"2022-06-30T14:53:28","slug":"how-to-tackle-current-and-future-pandemics-according-to-professor-william-stimson","status":"publish","type":"post","link":"https:\/\/mediahouseinternational.com\/how-to-tackle-current-and-future-pandemics-according-to-professor-william-stimson\/","title":{"rendered":"How to tackle current and future pandemics, according to Professor William Stimson"},"content":{"rendered":"

Professor William Stimson, founder and chief scientific officer of ILC Therapeutics, has penned an opinion piece in The Scotsman. The article<\/a>, which appeared in print and online, explores what we should be doing to prevent the world being held hostage again from another virus. Please read on. \u00a0<\/em><\/p>\n

As we live through the most rapidly evolving viral environment the world has seen, there is a critical need for effective and safe antiviral medicines to meet the challenges of today and the inevitable threats of tomorrow.<\/p>\n

Worldwide, we are searching for ways to inactivate major viruses \u2013 from influenza, HIV, HBV and coronaviruses such as Sars, Mers and Covid-19 \u2013 in order to reduce the unwanted responses associated with them.<\/p>\n

With regards to Covid-19, we have witnessed a Herculean effort in developing vaccines, and whilst the UK is arguably on its way to achieving \u2018endemic\u2019 status, the world is not remotely close to saying goodbye to this virus. It is here to stay and will likely remain a threat \u2013 perhaps not to everyone, but certainly to those with weakened immune systems, especially if it continues to mutate.<\/p>\n

From recent experience, we know that the emergence of new strains, and the questions that these mutations trigger, means that relying on a vaccine alone is not enough. Looking ahead, there is the risk of new coronaviruses and new global pandemics.<\/p>\n

Preventing a pandemic may not be possible, but the last couple of years has taught us that preparedness is key. We must focus on producing therapeutic solutions which can fight a virus as soon as there is an outbreak. That\u2019s where interferons come into play.<\/p>\n

Interferons are antiviral molecules that all humans produce, as do very many other organisms. They \u2018interfere\u2019 with viral reproduction and are the first to respond when an infection is detected to prevent the virus from replicating.<\/p>\n

They are key to the body\u2019s innate immune response, which is our first line of defence against invading pathogens, and also have strong links into adaptive immunity.<\/p>\n

These include synthetic therapeutic interferons which have shown great promise against Covid-19 in laboratory testing. Work at the University of St Andrews has led to the production of a wide-spectrum, antiviral biological drug called Alfacyte based on this concept by ILC Therapeutics. This drug essentially strengthens the \u2018wall\u2019 of the innate immune system to not let Covid-19 or other viruses through its barricade.<\/p>\n

Having a working therapeutic interferon, which accelerates the body\u2019s innate response to viral infection, could radically change future pandemic responses by acting as an immediate \u2018upstream\u2019 response to disease outbreak whilst more adapted \u2018downstream\u2019 solutions, such as vaccines, are developed. This could save many lives, prevent hospitalisations and reduce the need for aggressive social restrictions which have a high cost on society.<\/p>\n

We must be able to protect ourselves with an effective anti-viral therapeutic product, and we must be ready to deal with the next large-scale virus when it comes, especially as we wait for a vaccine. Investing in diverse and innovative treatments alongside vaccines with equal priority is the way forward.<\/p>\n

By doing so, we can achieve the therapeutic potential to prevent the world being held hostage again \u2013 whether by a future strain of Covid-19 or the next pandemic.<\/p>\n

 <\/p>\n","protected":false},"excerpt":{"rendered":"

Professor William Stimson, founder and chief scientific officer of ILC Therapeutics, has penned an opinion piece in The Scotsman. The article, which appeared in print and online, explores what we…<\/p>\n","protected":false},"author":2,"featured_media":16259,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[1],"tags":[],"acf":[],"_links":{"self":[{"href":"https:\/\/mediahouseinternational.com\/wp-json\/wp\/v2\/posts\/16257"}],"collection":[{"href":"https:\/\/mediahouseinternational.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/mediahouseinternational.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/mediahouseinternational.com\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/mediahouseinternational.com\/wp-json\/wp\/v2\/comments?post=16257"}],"version-history":[{"count":3,"href":"https:\/\/mediahouseinternational.com\/wp-json\/wp\/v2\/posts\/16257\/revisions"}],"predecessor-version":[{"id":16300,"href":"https:\/\/mediahouseinternational.com\/wp-json\/wp\/v2\/posts\/16257\/revisions\/16300"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/mediahouseinternational.com\/wp-json\/wp\/v2\/media\/16259"}],"wp:attachment":[{"href":"https:\/\/mediahouseinternational.com\/wp-json\/wp\/v2\/media?parent=16257"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/mediahouseinternational.com\/wp-json\/wp\/v2\/categories?post=16257"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/mediahouseinternational.com\/wp-json\/wp\/v2\/tags?post=16257"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}